Miniaturized analytical methods for determination of environmental contaminants of emerging concern – a reviewMiniaturized analytical methods for determination of environmental contaminants of emerging concern – a review Ανασκόπηση Review 2022-07-252021enThis article is based upon work from COST Action CA 16215, supported by COST (European Cooperation in Science and Technology) www.cost.eu. This article is based upon work from the Sample Preparation Study Group and Network, supported by the Division of Analytical Chemistry of the European Chemical Society. The corresponding authors thank the Spanish Ministry of Science, Innovation and Universities (Project RTI2018-093697-B-I00), the Spanish State Research Agency and FEDER for financial support. Z. Yang thanks UK NERC Fellowship grant (NE/R013349/2). M. A. Segundo acknowledges funding from Fundação para a Ciência e a Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior through grant UIDB/50006/2020.The determination of contaminants of emerging concern (CECs) in environmental samples has become a challenging and critical issue. The present work focuses on miniaturized analytical strategies reported in the literature for the determination of CECs. The first part of the review provides brief overview of CECs whose monitoring in environmental samples is of particular significance, namely personal care products, pharmaceuticals, endocrine disruptors, UV-filters, newly registered pesticides, illicit drugs, disinfection by-products, surfactants, high technology rare earth elements, and engineered nanomaterials. Besides, an overview of downsized sample preparation approaches reported in the literature for the determination of CECs in environmental samples is provided. Particularly, analytical methodologies involving microextraction approaches used for the enrichment of CECs are discussed. Both solid phase- and liquid phase-based microextraction techniques are highlighted devoting special attention to recently reported approaches. Special emphasis is placed on newly developed materials used for extraction purposes in microextraction techniques. In addition, recent contributions involving miniaturized analytical flow techniques for the determination of CECs are discussed. Besides, the strengths, weaknesses, opportunities and threats of point of need and portable devices have been identified and critically compared with chromatographic methods coupled to mass chromatography. Finally, challenging aspects regarding miniaturized analytical methods for determination of CECs are critically discussed.http://creativecommons.org/licenses/by-nc-nd/4.0/Analytica Chimica Acta1158Pena-Pereira_et_al_Anal. Chim. Acta_1158_2021.pdfChania [Greece]Library of TUC2022-07-25application/pdf4.2 MBfree Pena-Pereira Francisco Bendicho Carlos Pavlović Dragana Mutavdžić Martín-Esteban Antonio Díaz-Álvarez Myriam Pan Yuwei Cooper Jon Yang Zhugen Safarik Ivo Pospiskova Kristyna Segundo Marcela A. Psyllaki Eleftheria Ψυλλακη Ελευθερια Elsevier Emerging contaminants Microextraction Microfluidics Millifluidics Miniaturization Sample preparation