Abrupt events and population synchrony in the dynamics of Bovine TuberculosisAbrupt events and population synchrony in the dynamics of Bovine Tuberculosis Peer-Reviewed Journal Publication Δημοσίευση σε Περιοδικό με Κριτές 2019-05-232018enDisease control strategies can have both intended and unintended effects on the dynamics of infectious diseases. Routine testing for the harmful pathogen Bovine Tuberculosis (bTB) was suspended briefly during the foot and mouth disease epidemic of 2001 in Great Britain. Here we utilize bTB incidence data and mathematical models to demonstrate how a lapse in management can alter epidemiological parameters, including the rate of new infections and duration of infection cycles. Testing interruption shifted the dynamics from annual to 4-year cycles, and created long-lasting shifts in the spatial synchrony of new infections among regions of Great Britain. After annual testing was introduced in some GB regions, new infections have become more de-synchronised, a result also confirmed by a stochastic model. These results demonstrate that abrupt events can synchronise disease dynamics and that changes in the epidemiological parameters can lead to chaotic patterns, which are hard to be quantified, predicted, and controlled.http://creativecommons.org/licenses/by/4.0/Nature Communications91Moustakas_et_al_Nature Commun._9(1)_2018.pdfChania [Greece]Library of TUC2019-05-21application/pdf1.8 MBfree Moustakas Aristides Evans Matthew R. Daliakopoulos Ioannis Δαλιακοπουλος Ιωαννης Markonis Yannis Nature Publishing Group Disease control Infectious diseases Bovine Tuberculosis Incidence data Mathematical models Epidemiological parameters Abrupt events Disease dynamics