Comparison and unification of genomic signatures in breast cancerComparison and unification of genomic signatures in breast cancer Πλήρης Δημοσίευση σε Συνέδριο Conference Full Paper 2015-10-252009enThe concept of deriving a gene signature in breast cancer has been addressed by different research groups, each one proposing a different solution with minor overlap among them. There is still an open issue of unifying results among different research groups. In this study we evaluate two published signatures, namely the 70 gene signature of Netherlands group and a 57 gene signature published in our previous study and propose an evaluation platform under which the underlined signatures could be compared effectively. After such an evaluation, we proceed with a unified signature and assess its performance with improved efficiency over the initial signatures. http://creativecommons.org/licenses/by/4.0/3869-3872Annual International Conference of the IEEE Engineering in Medicine and Biology Society Zervakis Michail Ζερβακης Μιχαηλ Blazadonakis Michalis E. Institute of Electrical and Electronics Engineers Basic medical sciences Basic sciences, Medical Biomedical sciences Health sciences Preclinical sciences Sciences, Medical medical sciences basic medical sciences basic sciences medical biomedical sciences health sciences preclinical sciences sciences medical Genomics Bioinformatics Breast cancer Testing USA Councils Performance evaluation Neoplasms Helium Humans DNA