Estimation of time dependent virus inactivation rates by geostatistical and resampling techniques: Application to virus transport in porous mediaEstimation of time dependent virus inactivation rates by geostatistical and resampling techniques: Application to virus transport in porous media Peer-Reviewed Journal Publication Δημοσίευση σε Περιοδικό με Κριτές 2015-09-192004enA methodology is developed for estimating temporally variable virus inactivation rate coefficients from experimental virus inactivation data. The methodology consists of a technique for slope estimation of normalized virus inactivation data in conjunction with a resampling parameter estimation procedure. The slope estimation technique is based on a relatively flexible geostatistical method known as universal kriging. Drift coefficients are obtained by nonlinear fitting of bootstrap samples and the corresponding confidence intervals are obtained by bootstrap percentiles. The proposed methodology yields more accurate time dependent virus inactivation rate coefficients than those estimated by fitting virus inactivation data to a firstorder inactivation model. The methodology is successfully applied to a set of poliovirus batch inactivation data. Furthermore, the importance of accurate inactivation rate coefficient determination on virus transport in water saturated porous media is demonstrated with model simulationshttp://creativecommons.org/licenses/by/4.0/Stochastic Environmental Research and Risk Assessment18267-78A47-SERRA-04.pdfChania [Greece]Library of TUC2015-09-19application/pdf471.5 kBfree Chrysikopoulos Constantinos Χρυσικοπουλος Κωνσταντινος E. T. Vogler Virus transport in porous media Poliovirus inactivation