Ιδρυματικό Αποθετήριο [SANDBOX]
Πολυτεχνείο Κρήτης
EN  |  EL

Αναζήτηση

Πλοήγηση

Ο Χώρος μου

Improving the sensitivity of task-related Functional Magnetic Resonance Imaging data using generalized canonical correlation analysis

Kosteletou Emmanouela, Simos Panagiotis G., Kavroulakis Eleftherios, Antypa Despina, Maris Thomas G., Liavas Athanasios, Karakasis Paris, Papadaki Efrosini

Απλή Εγγραφή

URIhttp://purl.tuc.gr/dl/dias/0F72CCE3-7DD9-4A39-A7D5-7FC81DAF8554-
Αναγνωριστικόhttps://doi.org/10.3389/fnhum.2021.771668-
Αναγνωριστικόhttps://www.frontiersin.org/articles/10.3389/fnhum.2021.771668/full-
Γλώσσαen-
Μέγεθος11 pagesen
ΤίτλοςImproving the sensitivity of task-related Functional Magnetic Resonance Imaging data using generalized canonical correlation analysisen
ΔημιουργόςKosteletou Emmanouelaen
ΔημιουργόςSimos Panagiotis G.en
ΔημιουργόςKavroulakis Eleftheriosen
ΔημιουργόςAntypa Despinaen
ΔημιουργόςMaris Thomas G.en
ΔημιουργόςLiavas Athanasiosen
ΔημιουργόςΛιαβας Αθανασιοςel
ΔημιουργόςKarakasis Parisen
ΔημιουργόςΚαρακασης Παριςel
ΔημιουργόςPapadaki Efrosinien
ΕκδότηςFrontiers Mediaen
ΠερίληψηGeneral Linear Modeling (GLM) is the most commonly used method for signal detection in Functional Magnetic Resonance Imaging (fMRI) experiments, despite its main limitation of not taking into consideration common spatial dependencies between voxels. Multivariate analysis methods, such as Generalized Canonical Correlation Analysis (gCCA), have been increasingly employed in fMRI data analysis, due to their ability to overcome this limitation. This study, evaluates the improvement of sensitivity of the GLM, by applying gCCA to fMRI data after standard preprocessing steps. Data from a block-design fMRI experiment was used, where 25 healthy volunteers completed two action observation tasks at 1.5T. Whole brain analysis results indicated that the application of gCCA resulted in significantly higher intensity of activation in several regions in both tasks and helped reveal activation in the primary somatosensory and ventral premotor area, theoretically known to become engaged during action observation. In subject-level ROI analyses, gCCA improved the signal to noise ratio in the averaged timeseries in each preselected ROI, and resulted in increased extent of activation, although peak intensity was considerably higher in just two of them. In conclusion, gCCA is a promising method for improving the sensitivity of conventional statistical modeling in task related fMRI experiments.en
ΤύποςPeer-Reviewed Journal Publicationen
ΤύποςΔημοσίευση σε Περιοδικό με Κριτέςel
Άδεια Χρήσηςhttp://creativecommons.org/licenses/by/4.0/en
Ημερομηνία2022-08-04-
Ημερομηνία Δημοσίευσης2021-
Θεματική ΚατηγορίαTask-related fMRIen
Θεματική ΚατηγορίαSignal sensitivityen
Θεματική ΚατηγορίαfMRIen
Θεματική ΚατηγορίαgCCA methoden
Θεματική ΚατηγορίαAction observationen
Θεματική ΚατηγορίαSignal intensityen
Βιβλιογραφική ΑναφοράE. Kosteletou, P.G. Simos, E. Kavroulakis, D. Antypa, T. G. Maris, A. P. Liavas, P. A. Karakasis and E. Papadaki, “Improving the sensitivity of task-related Functional Magnetic Resonance Imaging data using generalized canonical correlation analysis,” Front. Hum. Neurosci., vol. 15, Dec. 2021, doi: 10.3389/fnhum.2021.771668.en

Διαθέσιμα αρχεία

Υπηρεσίες

Στατιστικά

 

Copyright © DIAS 2013