In our days the consequences of climate change are affecting many areas of people's lives, while creating difficulties in both ensuring human health and preserving the environment. Indeed, rising sea levels, global warming, floods, etc., along with the uncontrolled dimension of human economic activities have prompted institutions, cities and residents seeking to new proposals in order to strengthen the global response to climate change.A number of intervention strategies in response to climate change are constantly emerging, fueling the thinking of the above stakeholders and activating action plans. For example, through the smart city model, the strategy of developing city’s resilience but also mainly new trends such as the exploration of floating and submarine models of cities and innovation hubs, efforts are made to solve climate change issues with a more holistic approach over environment’s conservation. Therefore, aquatic environment seems to becoming more important as an experimentation location, as it solves a number of problems that have arisen on land, such as urban crowding, lack of flexibility in the structure’s movement, changing temperatures, sea level rising, etc.In this context, this research thesis attempts to study climate change in parallel with the trends of its solution, strategically and with emphasis on the aquatic environment, with the intention to develop a guide of good practices and contemporary for tackling climate change in the ocean. In order to achieve that goal the structure of the thesis is reflected in four parts. The first and second part concerns the research of definitions and effects of climate change in general and in relation to the water element. The third about world synergies and response policies in different countries about the phenomenon of climate change and the forth section presents a number of floating case studies from the international scene. A number of examples of floating cities, floating innovation hubs, underwater research centers, etc., is being analyzed, conveying the climate and direction of modern planning in the effort to cope climate change. Finally, the last part of the research thesis is attempted a collection and synthesis of design guides and conclusions, regarding the floating new cities and their future development on the occasion of the impacts of climate change.