Institutional Repository [SANDBOX]
Technical University of Crete
EN  |  EL

Search

Browse

My Space

Inter-subject variability of skull conductivity and thickness in calibrated realistic head models

Antonakakis Marios, Schrader Sophie, Aydin Ümit, Khan Asad, Gross Joachim, Zervakis Michail, Wolters Carsten H., Rampp, Stefan 1975-

Simple record


URIhttp://purl.tuc.gr/dl/dias/7B0FA8F8-7F2C-4ADF-9578-1A445728583F-
Identifierhttps://doi.org/10.1016/j.neuroimage.2020.117353-
Identifierhttps://www.sciencedirect.com/science/article/pii/S1053811920308399?via%3Dihub-
Languageen-
Extent14 pagesen
TitleInter-subject variability of skull conductivity and thickness in calibrated realistic head modelsen
CreatorAntonakakis Mariosen
CreatorΑντωνακακης Μαριοςel
CreatorSchrader Sophieen
CreatorAydin Ümiten
CreatorKhan Asaden
CreatorGross Joachimen
CreatorZervakis Michailen
CreatorΖερβακης Μιχαηλel
CreatorWolters Carsten H.en
CreatorRampp, Stefan 1975-en
PublisherElsevieren
Content SummarySkull conductivity has a substantial influence on EEG and combined EEG and MEG source analysis as well as on optimized transcranial electric stimulation. To overcome the use of standard literature values, we propose a non-invasive two-level calibration procedure to estimate skull conductivity individually in a group study with twenty healthy adults. Our procedure requires only an additional run of combined somatosensory evoked potential and field data, which can be easily integrated in EEG/MEG experiments. The calibration procedure uses the P20/N20 topographies and subject-specific realistic head models from MRI. We investigate the inter-subject variability of skull conductivity and relate it to skull thickness, age and gender of the subjects, to the individual scalp P20/N20 surface distance between the P20 potential peak and the N20 potential trough as well as to the individual source depth of the P20/N20 source. We found a considerable inter-subject variability for (calibrated) skull conductivity (8.44 ± 4.84 mS/m) and skull thickness (5.97 ± 1.19 mm) with a statistically significant correlation between them (rho = 0.52). Age showed a statistically significant negative correlation with skull conductivity (rho = -0.5). Furthermore, P20/N20 surface distance and source depth showed large inter-subject variability of 12.08 ± 3.21 cm and 15.45 ± 4.54 mm, respectively, but there was no significant correlation between them. We also found no significant differences among gender subgroups for the investigated measures. It is thus important to take the inter-subject variability of skull conductivity and thickness into account by means of using subject-specific calibrated realistic head modeling.en
Type of ItemPeer-Reviewed Journal Publicationen
Type of ItemΔημοσίευση σε Περιοδικό με Κριτέςel
Licensehttp://creativecommons.org/licenses/by/4.0/en
Date of Item2021-04-15-
Date of Publication2020-
SubjectSkull conductivityen
SubjectSkull thicknessen
SubjectEEG/MEG source analysisen
SubjectTranscranial electric stimulationen
SubjectCalibrated realistic head modelen
SubjectSomatosensory evoked responsesen
Bibliographic CitationM. Antonakakis, S. Schrader, Ü. Aydin, A. Khan, J. Gross, M. Zervakis, S. Rampp and C. H. Wolters, “Inter-subject variability of skull conductivity and thickness in calibrated realistic head models”, NeuroImage, vol. 223, Dec. 2020. doi: 10.1016/j.neuroimage.2020.117353en

Available Files

Services

Statistics