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Ιδρυματικό Αποθετήριο [SANDBOX]
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| URI | http://purl.tuc.gr/dl/dias/BAFF2314-4953-4606-8B04-2F2565A0D994 | - |
| Αναγνωριστικό | http://www.aaqr.org/article/detail/AAQR-15-09-OA-0536 | - |
| Αναγνωριστικό | https://doi.org/10.4209/aaqr.2015.09.0536 | - |
| Γλώσσα | en | - |
| Μέγεθος | 12 pages | en |
| Τίτλος | Personal exposure and dose of inhaled ambient particulate matter bound metals in five european cities | en |
| Δημιουργός | Mammi-Galani Eleni | en |
| Δημιουργός | Μαμμη-Γαλανη Ελενη | el |
| Δημιουργός | Chalvatzaki Eleftheria | en |
| Δημιουργός | Χαλβατζακη Ελευθερια | el |
| Δημιουργός | Lazaridis Michail | en |
| Δημιουργός | Λαζαριδης Μιχαηλ | el |
| Εκδότης | AAGR Aerosol and Air Quality Research | en |
| Περίληψη | The objective of the current study is the determination of the personal exposure and dose of ambient particulate matterbound metals in human tissues at five European cities. The accumulation in human body of lead (Pb), arsenic (As) and cadmium (Cd), in five European cities (Athens, Seville, Rome, Frankfurt and Zabrze) was calculated using an exposure and dose assessment model, ExDoM, and a pharmacokinetic model, PBPK. The study subjects are adult Caucasian nonsmoker males. It was calculated that the highest dose of particulate matter is received from a resident of Seville, due to the higher ambient PM10 levels in the city compared to the other sites. First, the current study showed that the European Union thresholds of particle-bound Pb, Cd and As concentrations were not exceeded in the cities under study. As regard the dose of Pb and As the higher dose is calculated for Athens and Seville, respectively. The highest dose of Cd is found at Zabrze, due to the high industrial activity in the city. It was calculated that after one day of exposure, the highest accumulation of Pb occurred in blood, muscles and bones. Furthermore, the highest deposition of Cd occurred in the lungs and intestines and for As in the lung and muscles. The heavy metals intake, calculated in this study, was very low in comparison with the recommended WHO levels for heavy metals intake from all types of exposure (inhalation, ingestion). | en |
| Τύπος | Peer-Reviewed Journal Publication | en |
| Τύπος | Δημοσίευση σε Περιοδικό με Κριτές | el |
| Άδεια Χρήσης | http://creativecommons.org/licenses/by/4.0/ | en |
| Ημερομηνία | 2018-10-12 | - |
| Ημερομηνία Δημοσίευσης | 2016 | - |
| Θεματική Κατηγορία | Exposure modelling | en |
| Θεματική Κατηγορία | Human exposure | en |
| Θεματική Κατηγορία | Human metal dose | en |
| Θεματική Κατηγορία | PBPK model | en |
| Θεματική Κατηγορία | Respiratory tract model | en |
| Βιβλιογραφική Αναφορά | E. Mammi-Galani, E. Chalvatzaki and M. Lazaridis, "Personal exposure and dose of inhaled ambient particulate matter bound metals in five european cities," Aerosol Air Qual. Res., vol. 16, no. 6, pp. 1452-1463, Jun. 2016. doi: 10.4209/aaqr.2015.09.0536 | en |
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