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Evaluation of short- and long-term response to treatment in GIMEMA protocol for acute myeloid leukaemia

Zervakis Michail, Kounelakis M. G., Manikis G., Iacobelli, Silvia, Ardoino I., Boracchi P., Lisboa P.J.G.

Πλήρης Εγγραφή

URI: http://purl.tuc.gr/dl/dias/3CB4A03C-9D1E-4BB7-A8A2-3503C6B2AEEC
Έτος 2010
Τύπος Δημοσίευση σε Περιοδικό με Κριτές
Άδεια Χρήσης
Λεπτομέρειες
Βιβλιογραφική Αναφορά I. Ardoino, F. Ambrogi, S. Iacobelli, P. Boracchi, G. Manikis, M.G. Kounelakis, M. Zervakis, P.J.G. Lisboa, P. Fazi, M. Vignetti, E. M. Biganzoli and A. Starita, "Evaluation of short- and long-term response to treatment in GIMEMA protocol for acute myeloid leukaemia, "Intern. J. of Biomedical Eng. Techn., vol.3, no.3-4, pp.329-348. doi: 10.1504/IJBET.2010.032699 https://doi.org/10.1504/IJBET.2010.032699
Εμφανίζεται στις Συλλογές
Δημοσιεύσεις σε Περιοδικά στην Κοινότητα Σχολή Ηλεκτρολόγων Μηχανικών και Μηχανικών Υπολογιστών

Περίληψη

Acute Myeloid Leukaemia (AML) is a haematologic malignancy. Despite of improvements in prognosis it is still a severe disease and only a minority of patients are cured. Recently, insights into specific cytogenetics and biological aberration involved in the leukaemogenesis process are the target of research. LAM-99P GIMEMA Protocol identifies treatment guidelines for AML in adults. A methodological approach is proposed, compounding different modelling techniques, to assess the prognostic relevance of clinical as well as biological markers with regard to clinical endpoint, such as the achievement of Complete Remission in the short-term and long-term survival taking into account competing risks.

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