Το έργο με τίτλο CXCR4 pathways in CTCs: from bioinformatics to immunophenotype από τον/τους δημιουργό/ούς D. Mavroudis, G. Kallergi, S. Sfakianakis, V. Georgoulias, Zervakis Michalis διατίθεται με την άδεια Creative Commons Αναφορά Δημιουργού 4.0 Διεθνές
Βιβλιογραφική Αναφορά
G. Kallergi, V. Tsintari, S. Sfakianakis, M. Zervakis, D. Mavroudis, V. Georgoulias ,"CXCR4 pathways in CTCs: from bioinformatics to immunophenotype,"Cancer Res.,vol.75,no.15, pp.1592-1592,2015.doi:10.1158/1538-7445.AM2015-1592
https://doi.org/10.1158/1538-7445.AM2015-1592
Bioinformatics' analysis regarding gene expression in Normal tissue vs cancer tissue, Normal blood vs cancer patients' blood and Normal blood vs cancer tissue revealed a subgroup of 24 genes which potentially could be overexpressed in CTCs. Among these genes are: CXCR4, a chemokine receptor which is involved in tumor metastasis and, JUNB a transcription factor participating in CXCR4 pathway.