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Potential dementia biomarkers based on the time-varying microstructure of sleep EEG spindles

Zervakis Michalis, Golemati, S, H. Tsekou , Paparrigopoulos, T

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URIhttp://purl.tuc.gr/dl/dias/FFFCCE6A-66F8-4782-9D7F-5F9BF087B4F8-
Identifierhttps://doi.org/10.1109/IEMBS.2007.4352827-
Languageen-
Extent4 pagesen
TitlePotential dementia biomarkers based on the time-varying microstructure of sleep EEG spindlesen
CreatorZervakis Michalisen
CreatorΖερβακης Μιχαληςel
CreatorGolemati, Sen
CreatorH. Tsekou en
CreatorPaparrigopoulos, Ten
PublisherInstitute of Electrical and Electronics Engineersen
Content SummaryThe time-varying microstructure of sleep EEG spindles may have clinical significance in dementia studies. In this work, the sleep spindle is modeled as an AM-FM signal and parameterized in terms of six parameters, three quantifying the instantaneous envelope (IE) and three quantifying the instantaneous frequency (IF) of the spindle model. The IE and IF waveforms of sleep spindles from patients with dementia and normal controls were estimated using the time-frequency technique of complex demodulation (CD). Sinusoidal curve-fitting using a matching pursuit (MP) approach was applied to the IE and IF waveforms for the estimation of the six model parameters. Specific differences were found in sleep spindle instantaneous frequency dynamics between spindles from dementia subjects and spindles from controls. en
Type of ItemΑφίσα σε Συνέδριοel
Type of ItemConference Posteren
Licensehttp://creativecommons.org/licenses/by/4.0/en
Date of Item2015-10-23-
Date of Publication2007-
SubjectClinical laboratory techniciansen
SubjectMedical laboratory techniciansen
Subjectmedical technologistsen
Subjectclinical laboratory techniciansen
Subjectmedical laboratory techniciansen
Bibliographic CitationP.Y. Ktonas, S. Golemati, H. Tsekou, T. Paparrigopoulos, C.R.Soldatos ," Potential dementia biomarkers based on the time-varying microstructure of sleep EEG spindles ," in 2007 29th Annual Inter. Conf. of the IEEE Eng. in Medicine and Biology Society, EMBS ,pp.2464 - 2467.doi:10.1109/IEMBS.2007.4352827en

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