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Time-significant wavelet coherence for the evaluation of schizophrenic brain activity using a graph theory approach

Zervakis Michalis, Sakkalis, Vangelis, S.Micheloyannis, E.Pachou

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URIhttp://purl.tuc.gr/dl/dias/0BCB23B2-09AA-4EF9-AF16-531C3DF17AF0-
Αναγνωριστικόhttps://doi.org/10.1109/IEMBS.2006.260680-
Γλώσσαen-
Μέγεθος4 pagesen
ΤίτλοςTime-significant wavelet coherence for the evaluation of schizophrenic brain activity using a graph theory approachel
ΔημιουργόςZervakis Michalisen
ΔημιουργόςΖερβακης Μιχαληςel
ΔημιουργόςSakkalis, Vangelisen
ΔημιουργόςS.Micheloyannisen
ΔημιουργόςE.Pachou en
ΕκδότηςInstitute of Electrical and Electronics Engineersen
ΠερίληψηAmong the various frameworks in which electroencephalographic (EEG) signal synchronization has been traditionally formulated, the most widely studied and used is the coherence that is entirely based on frequency analysis. However, at present time it is possible to capture information about the temporal profile of coherence, which is particularly helpful in studying non-stationary time-varying brain dynamics, like the wavelet coherence (WC). In this paper we propose a new approach of studying brain synchronization dynamics by extending the use of WC to include certain statistically significant (in terms of signal coherence) time segments, to study and characterize any disturbances present in the functional connectivity network of schizophrenia patients. Graph theoretical measures and visualization provide the tools to study the "disconnection syndrome" as proposed for schizophrenia. Specifically, we analyzed multichannel EEG data from twenty stabilized patients with schizophrenia and controls in an experiment of working memory (WM) using the gamma band (i.e., the EEG frequency of ca. 40 Hz), which is activated during the connecting activity (i.e., the "binding" of the neurons). The results are in accordance with the disturbance of connections between the neurons giving additional information related to the localization of most prominent disconnectionen
ΤύποςΠλήρης Δημοσίευση σε Συνέδριοel
ΤύποςConference Full Paperen
Άδεια Χρήσηςhttp://creativecommons.org/licenses/by/4.0/en
Ημερομηνία2015-10-23-
Ημερομηνία Δημοσίευσης2006-
Βιβλιογραφική ΑναφοράV. Sakkalis, T. Oikonomou, E. Pachou, I. Tollis, S. Micheloyannis, M. Zervakis ," Time-significant wavelet coherence for the evaluation of schizophrenic brain activity using a graph theory approach,"in 2006 28th Annual Intern. Conf. of the IEEEE eng. in Medicine and Biol. Society,pp.4265 - 4268.doi:10.1109/IEMBS.2006.260680en

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