Institutional Repository [SANDBOX]
Technical University of Crete
EN  |  EL

Search

Browse

My Space

Synthesis of quinoxalines by cyclization of α-arylimino oximes of α-dicarbonyl compounds

Xekoukoulotakis Nikos, A.J Maroulis, C.P Hadjiantoniou-Maroulis

Full record


URI: http://purl.tuc.gr/dl/dias/B90E479C-48D7-4FC2-A16E-91B416B5ED71
Year 2000
Type of Item Peer-Reviewed Journal Publication
License
Details
Bibliographic Citation N.P. Xekoukoulotakis, C.P. Hadjiantoniou-Maroulis and A.J. Maroulis, Synthesis of quinoxalines by cyclization of α-arylimino oximes of α-dicarbonyl compounds, Tetrahedron Letters, Vol. 41, no.52, pp. 10299-10302, Dec. 2000. doi:10.1016/S0040-4039(00)01847-5 https://doi.org/10.1016/S0040-4039(00)01847-5
Appears in Collections

Summary

Heating the title compounds 1 at reflux in acetic anhydride yields quinoxalines 3 and 4 via a presumed aryliminoiminyl radical 5, resulting from homolytic cleavage of the NO bond in the intermediate ester 2. The observed regioselectivity of the reaction is also rationalized by implicating such a radical.

Services

Statistics