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Oxygenation capabilities of basket-type bioreactors for microcarrier cultures of anchorage-dependent cells

Kalogerakis Nikos, Behie L.A.

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URIhttp://purl.tuc.gr/dl/dias/0A87B318-1134-46BF-9BE1-06C3488F3F81-
Identifierhttps://doi.org/10.1007/s004490050369-
Languageen-
Extent5en
TitleOxygenation capabilities of basket-type bioreactors for microcarrier cultures of anchorage-dependent cellsen
CreatorKalogerakis Nikosen
CreatorΚαλογερακης Νικοςel
CreatorBehie L.A. en
DescriptionΔημοσίευση σε επιστημονικό περιοδικό el
Content SummaryThe oxygenation capabilities of a new generation three phase - two region 1200 l bioreactor employed for the cultivation of anchorage dependent animal cells were investigated experimentally. A mathematical model has also been developed that explains qualitatively the observed oxygenation characteristics. This type of bioreactor, that uses microcarrier support particles, has two distinct mesh-separated regions so that the air bubbles in the oxygenation region do not come into contact with the microcarriers in the cell (bubble-free) region. Implications on achievable maximum cell densities are also discussed. en
Type of ItemPeer-Reviewed Journal Publicationen
Type of ItemΔημοσίευση σε Περιοδικό με Κριτέςel
Licensehttp://creativecommons.org/licenses/by/4.0/en
Date of Item2015-10-19-
Date of Publication1997-
Subject1200 l bioreactor en
Subjectanimal cellsen
Subjectoxygenation en
Bibliographic CitationN. Kalogerakis, and L.A. Behie,"Oxygenation capabilities of basket-type bioreactors for microcarrier cultures of anchorage-dependent cells," Bioprocess and Biosystems Engineering, vol. 17, no. 3, pp. 151-156, Jul. 1997. doi: 10.1007/s004490050369en

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