URI | http://purl.tuc.gr/dl/dias/1D12D20F-0909-4549-AAB8-B5C8C5E0641C | - |
Identifier | https://doi.org/10.1007/s00477-003-0130-z | - |
Language | en | - |
Extent | 12 pages | en |
Title | Estimation of time dependent virus inactivation rates by geostatistical and resampling techniques: Application to virus transport in porous media | en |
Creator | Chrysikopoulos Constantinos | en |
Creator | Χρυσικοπουλος Κωνσταντινος | el |
Creator | E. T. Vogler | en |
Content Summary | A methodology is developed for estimating
temporally variable virus inactivation rate coefficients
from experimental virus inactivation data. The methodology
consists of a technique for slope estimation of
normalized virus inactivation data in conjunction with
a resampling parameter estimation procedure. The
slope estimation technique is based on a relatively
flexible geostatistical method known as universal kriging.
Drift coefficients are obtained by nonlinear fitting
of bootstrap samples and the corresponding confidence
intervals are obtained by bootstrap percentiles. The
proposed methodology yields more accurate time dependent
virus inactivation rate coefficients than those
estimated by fitting virus inactivation data to a firstorder
inactivation model. The methodology is successfully
applied to a set of poliovirus batch inactivation
data. Furthermore, the importance of accurate inactivation
rate coefficient determination on virus transport
in water saturated porous media is demonstrated with
model simulations | en |
Type of Item | Peer-Reviewed Journal Publication | en |
Type of Item | Δημοσίευση σε Περιοδικό με Κριτές | el |
License | http://creativecommons.org/licenses/by/4.0/ | en |
Date of Item | 2015-09-19 | - |
Date of Publication | 2004 | - |
Subject | Virus transport in porous media | en |
Subject | Poliovirus inactivation | en |
Bibliographic Citation | C. V. Chrysikopoulos,E. T. Vogler, "Estimation of time dependent virus inactivation rates by geostatistical and resampling techniques: application to virus transport in porous media", Stoch. Environ.Res. ,vol. 18,no.2 ,pp. 67 – 78,2004.doi10.1007/s00477-003-0130-z | en |