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Estimation of time dependent virus inactivation rates by geostatistical and resampling techniques: Application to virus transport in porous media

Chrysikopoulos Constantinos, E. T. Vogler

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URIhttp://purl.tuc.gr/dl/dias/1D12D20F-0909-4549-AAB8-B5C8C5E0641C-
Identifierhttps://doi.org/10.1007/s00477-003-0130-z -
Languageen-
Extent12 pagesen
TitleEstimation of time dependent virus inactivation rates by geostatistical and resampling techniques: Application to virus transport in porous mediaen
CreatorChrysikopoulos Constantinosen
CreatorΧρυσικοπουλος Κωνσταντινοςel
CreatorE. T. Vogleren
Content SummaryA methodology is developed for estimating temporally variable virus inactivation rate coefficients from experimental virus inactivation data. The methodology consists of a technique for slope estimation of normalized virus inactivation data in conjunction with a resampling parameter estimation procedure. The slope estimation technique is based on a relatively flexible geostatistical method known as universal kriging. Drift coefficients are obtained by nonlinear fitting of bootstrap samples and the corresponding confidence intervals are obtained by bootstrap percentiles. The proposed methodology yields more accurate time dependent virus inactivation rate coefficients than those estimated by fitting virus inactivation data to a firstorder inactivation model. The methodology is successfully applied to a set of poliovirus batch inactivation data. Furthermore, the importance of accurate inactivation rate coefficient determination on virus transport in water saturated porous media is demonstrated with model simulationsen
Type of ItemPeer-Reviewed Journal Publicationen
Type of ItemΔημοσίευση σε Περιοδικό με Κριτέςel
Licensehttp://creativecommons.org/licenses/by/4.0/en
Date of Item2015-09-19-
Date of Publication2004-
Subject Virus transport in porous mediaen
Subject Poliovirus inactivationen
Bibliographic CitationC. V. Chrysikopoulos,E. T. Vogler, "Estimation of time dependent virus inactivation rates by geostatistical and resampling techniques: application to virus transport in porous media", Stoch. Environ.Res. ,vol. 18,no.2 ,pp. 67 – 78,2004.doi10.1007/s00477-003-0130-zen

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